Coenzyme Q10 (or just Q10) is a vitamin-like substance. It's also called ubiqinon (ubi is Latin and means ”everywhere”). Bio-Quinon Q10 Gold contains vitamin C that contributes to a normal energy-yielding metabolism. When a cell needs energy it convert fat, carbohydrate, protein, and alcohol to the ATP (adenosine triphosphate), a molecule that stores energy in its chemical form. The cell breaks down the ATP molecule and releases the energy trapped inside. The entire process takes place inside the cells in some small bean-shaped structures called mitochondria. In all mitochondria coenzyme Q10 is found. Muscle cells are particularly dependent on large amounts of energy, which is why muscle cells contain substantially more mitochondria than other types of cells. The heart muscle is a good example of body tissue with cells that contain a large number of mitochondria and have a correspondingly large energy requirement. Good Q10 sources
We get Q10 from several types of food, some of the best sources of Q10 in food are::
In addition, humans are able to synthesize Q10 in the body. The process, which takes place in the liver, slows down as we grow older and as a result of disease. According to experts, the body’s Q10 levels peak at the age of 20-25 years from which point it begins on a downward slope.
Science has not been able to quantify exactly how much Q10 is provided by means of the diet but it is estimated to be somewhere around 5-20 mg daily. The body has a Q10 reserve that amounts to about 1 – 1.5 grams. The highest concentrations are found in the heart, liver, and kidneys. Big difference in Q10 products
Pharma Nord has spent more than 20 years documenting the absorbability, effectiveness, and safety of the product Bio-Quinone Q10. But many Q10 products are currently sold without any documentation which may give the user assurance of an effect. In the wake of this a number of claims has emerged about what kind of Q10 is best. A team of U.S. Researchers has reviewed and weeded out the false claims. What remains are the facts about the effect and use of Q10. Unprocessed Q10 poorly absorbed
Optimum absorbability has been the keyword in the development of bio-Quinone Q10, and this is documented in approx. 40 scientific studies. One of the biggest challenges associated with Q10 as a supplement is that the substance generally is not readily absorbed by the body. Q10 in other words, has a low bioavailability. The Q10 molecule is a relatively large molecule and this is the main reason for its poor absorbtion in the body and as a result of its molecular structure, it is fat soluble. Slowly release into the blood
Q10 is absorbed in the intestinal wall along with fat and is then transported by the lymph wessels to the subclavian vein, where it emptied into the venous blood. This slow mode of transport results in a maximum concentration of Q10 in the blood 6-8 hours after ingestion. Therefore, it is preferable to take Q10 with breakfast or perhaps lunch. If you take more than 1 capsule daily, the effect is larger by spreading the dose throughout the day - eg. one capsule at breakfast and one capsule at lunch time - rather than taking the the daily dosage at once. Crystals are not absorbed
A Bio-Quinone Q10 capsule contains a special oil matrix in which the substance Q10 is in a molecular form. The starting point for all products is the Q10 raw material consisting of crystals, which in practice are not absorbed by the body. Q10 must be dissolved into single Q10 molecules before they can be absorbed. Less than 1% of Q10 is absorbed from products solely consisting of crystalline Q10, typically tablet products and hard capsules using unprocessed Q10 crystals. The crystals may be dissolved by using a special oil mixture, and a subsequent heating method, thereby, releasing Q10 into single molecules, which provides a quick and good absorption with oil. Q10 always fat-soluble
A marketing strategy has gone on to claim that it is better to make Q10 water soluble, but neither a change to the Q10 molecule or placement of the fat-soluble Q10 molecules in liposomes (small spheres with an outer fatty membrane and an inner aqueous membrane) or linking Q10 to micelles (small spheres with a fatty core and a water-loving surface) or attaching nano-particles to Q10 will make the Q10 molecule more water soluble. If you try, you just end up with an even bigger Q10 molecule complex, but no increased bioavailability and the Q10 molecule will still predominantly be fat soluble. If you choose to go the opposite way and make the molecule smaller, this will surely make the molecule more water soluble and more absorbable, but such a reduced molecule will no longer be Q10, but would be reduced to Q9 or Q8 which is of no value to humans. Most documentation on Ubiqinon
Q10 is found in two forms. An oxidized form called ubiqinon as well as a reduced form called ubiquinol. Ubiquinol is also called active Q10. The kind of Q10 we produce in the liver is the oxidized ubiqinon. Q10 from our food is also the oxidized form. In the lymphatic system or the blood oxidized Q10 is changed to active Q10. Therefore, the 90-95% of blood Q10 is the active form. In the cells' energy-producing mitochondria Q10 continuously is shifting between these two forms, a property which is crucial for Q10s effects in the body.
Therefore, it is makes no difference what form you consume, your body will still convert oxidized Q10 into active Q10. To date, almost all evidence of efficacy and safety are done with the oxidized form, ubiqinon. Ubiqinon = oxidized Q10 = ordinary Q10 Ubiqinol = reduced Q10 = active Q10