can be used in situations of stress and fatigue. Favorable for the muscles. Magnesium glycerophosphate is a fat-soluble magnesium salt which is absorbed well and causes practically no digestive disorders. Magnesium is a key element of bio-energetics. It catalyses numerous enzyme functions. Magnesium deficiency may lead to an enhanced excretion of adrenalin and noradrenalin, responsible for an increased alarm reaction. In the central nervous system, a physiological concentration of magnesium controls the activity of the NMDA- receptors (N-Methyl-D-Aspartate). Their activation is responsible for the LTP (Long Term Potentialisation). A decreased control of the NMDA- receptors partially explains the hyperactivity of the nerves, observed in case of magnesium deficiency.
Magnesium is important in control of muscle relaxation as well.
Besides its supportive function on the neuromuscular over-irritability,
magnesium is essential to obtain the active forms of vitamin B.
Vitamin B6, the need of which is increased in case of tensions and pill
usage, plays a role in the synthesis of 2 neurotransmitters: serotonine and GABA. Both play an important role in modulating the alarm reaction of the nervous system. Folate (vit. B9) and vitamin B12 are essential for the methylation reactions and especially play a role in the synthesis of tetrabiopterin, an important co-factor of the serotonine synthesis.
MetaRelax contains an active form of folate, calcium-L-methyl folate, which is immediately bio-available, as opposed to with folic acid, which is a pro-vitamin that needs to be activated. Hence, it is also readily available by the body, regardless of the genetic variation in folate dependent enzymes. Calcium-L-methyl folate is the only form that is able to pass through the blood-brain barrier.
Taurine, derived from cystein through the activity of a vitamin B6 using enzyme, is a conditional essential amino acid. By stabilizing the cell membranes, taurine contributes to the saving of magnesium in the cells. Just as magnesium, it decreases the amount of adrenalin excreted by the adrenals during stress.