Description of Fertility Woman Duo Omarin + Improve
Dietary supplements and infertility
It has become clear that not only men but also women have infertility problems.
Since the fifties scientific data have been available on the relation between the factors determining ovum quality, and those necessary for optimal fertility levels. Usually this is technically solved through a number of techniques such as IVF (in vitro fertilization) or ICSI (intracellular sperm injection). Recently however, a number of side-effects of IVF have come to light such as an increased prevalence of major congenital malformations, impaired development, and increased risk of retinoblastoma in the offspring.
Female infertility: a multifactorial disease
Similar to other diseases male infertility comes to expression as a result of the synergistic coincidence of four major factors: genetic defects or constitution, life style factors, professional and / or environmental exposure and diseases of the urethrogenital region or endocrine system. The field of genetics is rapidly expanding and includes numerical and structural abnormalities of the chromosomal make-up as well as microdeletions of the Y chromosome. Whether or not certain of these minor deletions will cause infertility may depend on the coincidental presence of unfavourable life-style factors or exposure to toxic substances or hormone disrupters. These and the genital diseases have been shown to increase the load of reactive oxygen species to the ovum, resulting in increased chromosome fractionation and excessive production of oxidized DNA. Oxidative overload also changes the phospholipid composition of the ovum membrane, reducing its fluidity and fusogenic capacity as well as the induced acrosome reactivity. Connections have been found between nutrition and drug abuse, but also environmental circumstances. Lower ovum quality is caused by a number of factors including toxicants such heavy metals (lead, cadmium, mercury, (...)) but especially by xeno-oestrogens. Xeno-oestrogens are artificial chemical substances that mimic or enhance the effects of oestrogens by binding on the human oestrogen receptor or by influencing oestrogen metabolism.
Fatty acids: The presence of DHA is crucial for the integrity and fluidity of the ovum membrane. Namely ecosapantaenoic acid and docosahexaenoic acid. The latter increase the fluidity of the membrane, improving the induced acrosome reaction and fusogenic capacity of the spermatozoa.
Antioxidants: It has been shown that treatment with either acetyl carnitine or an antioxidant mixture of β-carotene and α-tocopherol significantly reduces the level of reactive oxygen species in the ovum. ROS is a important groupe of free radicals who cause damage to the ovum. L-carnitine (an amino acid) plays - together with coenzyme Q10 – an important role in the energy production in cells and therefore also in egg-cells. Carnitine also positively affects sperm motility. B vitamins are also important for the energy production.
Folic acid and zinc: Folic acid plays an important role in the prevention of spina bifide, but also in the production of energy. Zinc also plays an important role in the noradrenaline and testosterone production by the adrenal glands for a healthy immune system. And testosterone seems to be of vital importance for the libido, both in women and men.
Plant extracts: The Pinus maritima bark extract improves the peripheral blood saturation. Lepidium meyenii (maca), a plant growing in the central Andean region of Peru between 4000 and 4500 m altitude, increases sexual function and invigorates the ovum production at the mitotic stages. This means that more and more evidence-based material is available showing that ovum quality can be improved after intake of specific nutrients and those specific nutrients are present in Improve®.
Product description Omarin®:
Omarin® (oil capsules) is a fish oil with a high concentration of the polyunsaturated omega–3 fatty acids EPA (eicosapentaen acid, 33%) and DHA (docosahexaen acid, 22%). To this combination of omega-3 fatty acids natural vitamin E (D-α-tocopherol) has been added to prevent oxidation of the oil. The fatty acids in Omarin®are called essential because they can only be obtained through nutrition. However, research shows that our western diet is poor in fatty acids. Omega-3 fatty acids have many functions in the human body: optimizing LDL- and HDL-cholesterol, triglycerid and fibrinogen concentrations, stimulation of supple muscles and joints. Omarin®is also an ideal source of omega-3 fatty acids for pregnant women, especially during the first three months of the pregancy when the fetal nervous system is developed. Tests show that the omega-3 fatty acids in Omarin®are free of heavy metals and dioxins.
Ingredients Fertility Woman Duo Omarin + Improve
-Lepidium meyenii (Maca) 125 mg
-Pinus maritima 50 mg
-Acetyl-L-carnitine 50 mg
-Coenzyme Q10 12.5 mg
-Astaxanthin 4 mg
-Zinc bisglycinate 3.75 mg
-Vitamin B6 1.5 mg
-Vitamin B9 0.1 mg
-Vitamin B12 0.75 µg
-Omega-3 fatty acids including:
- DHA (22%)
- EPA (33%) 1000 mg
Natural vitamin E 5 mg